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Research status of visuospatial dysfunction and spatial navigation
Visuospatial function is a critical aspect of cognitive abilities, encompassing visual perception, attention, memory, and adaptive responses to spatial changes. This paper reviews studies on human visuospatial function, spatial navigation, and factors contributing to visuospatial impairments. After introducing fundamental concepts of visuospatial function and spatial navigation, classical methods for assessing visuospatial performance are summarized. By examining recent advances in spatial...
Intervention strategies for Parkinson's disease: the role of exercise and mitochondria
Parkinson's disease (PD), a progressive neurodegenerative disorder with complex pathogenic mechanisms, exhibiting rising prevalence alongside global population aging. Its pathological hallmarks include substantial loss of dopaminergic neurons in the substantia nigra pars compacta, leading to motor symptoms (e.g., bradykinesia, rigidity) and non-motor manifestations (e.g., cognitive impairment, sleep disorders). Accumulating evidence underscores mitochondrial dysfunction-encompassing reactive...
Unravelling the interplay: brain regional atrophy and neuropsychological function in early Alzheimer's disease
CONCLUSION: In patients with AD, the results of most cognitive function tests are related to the degree of atrophy of the temporal and frontal cortices. Further research is necessary to determine the extent to which cognitive function test results are associated with brain atrophy.
Daily briefing: Immune cell ‘spies’ give the brain information about the gut
‘Scienticide’ in Argentina sparks huge protest by researchers
Black Death bacterium has become less lethal after genetic tweak
Predicting and preventing Alzheimer’s disease
Science, Volume 388, Issue 6750, May 2025.
Erratum for the Research Article “Hydro-locking in hydrogel for extreme temperature tolerance” by X. Zhang et al.
Science, Volume 388, Issue 6750, May 2025.
Erratum for the Research Article “High cooling performance in a double-loop electrocaloric heat pump” by J. Li et al.
Science, Volume 388, Issue 6750, May 2025.
Ecological and evolutionary consequences of changing seasonality
Science, Volume 388, Issue 6750, May 2025.
Functional polymorphism of CYCLE underlies the diapause variation in moths
Science, Volume 388, Issue 6750, May 2025.
Attenuation of virulence in Yersinia pestis across three plague pandemics
Science, Volume 388, Issue 6750, May 2025.
A single domestication origin of adzuki bean in Japan and the evolution of domestication genes
Science, Volume 388, Issue 6750, May 2025.
Prehistoric genomes from Yunnan reveal ancestry related to Tibetans and Austroasiatic speakers
Science, Volume 388, Issue 6750, May 2025.
BRAF oncogenic mutants evade autoinhibition through a common mechanism
Science, Volume 388, Issue 6750, May 2025.