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Daily briefing: What science photos do that AI-generated images can’t
UK PhD students welcome 8% pay boost, but demand more to meet rising living costs
Postdocs and PhD students hit hard by Trump’s crackdown on science
Breast cancer is on the rise: data reveal drastic gap in survival rates
Ancient apex predator tore into hippos with hyena-like teeth
Author Correction: The Ronne Ice Shelf survived the last interglacial
Restoring the primary cilia–autophagy axis in neurons to foster cognitive resilience
What makes biological age epigenetic clocks tick
The racial injustice laid bare by COVID must not be forgotten
Trekking across Nepal to bridge its gender gap in the sciences
Will AI jeopardize science photography? There’s still time to create an ethical code of conduct
How scientists can drive climate action: celebrate nature and promote hope
Chasing wildcats with my daughter
Author Correction: HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes
NASA cuts off international climate science support
U.N. panel meets for first time without U.S. leadership
Unusual ‘soda lakes’ may have kick-started life on Earth by concentrating key compounds
Phosphorus leached from volcanic rocks in warm waters could have triggered reactions needed to launch biochemistry
U.S. gene banks, key to new crops, hobbled by Trump job cuts
Newly appointed head of USDA’s genetic repositories axed along with key staff
Attila’s Huns were a motley crew of central European locals and East Asian immigrants
A genetic analysis reveals some Huns descended from pillagers in East Asia
A scientific field, misledDoctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Charles Piller Atria/One Signal, 2025. 352 pp
Fraud undermines Alzheimer's disease research.
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration
Myxomatous mitral valve degeneration (MMVD) is one of the most important age-dependent degenerative heart valve disorders in both humans and dogs. It is characterized by the aberrant remodeling of extracellular matrix (ECM), regulated by senescent myofibroblasts (aVICs) transitioning from quiescent valve interstitial cells (qVICs), primarily under TGFB1/TGF-β1 control. In the present study, we found senescent aVICs exhibited impaired macroautophagy/autophagy as evidenced by compromised autophagy...