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The complex interplay between aging and cancer
Mouse with a mammoth’s pelt makes superfuzzy debut
Birth of rodent with coat genetically modified to resemble the extinct species raises big ethical and conservation concerns
We moved a conference halfway around the globe to avoid visa discrimination
Train clinical AI to reason like a team of doctors
Three AI-powered steps to faster, smarter peer review
The science of shopping addiction: what makes people buy loads of stuff?
China’s supreme court calls for crack down on paper mills
AI must be taught concepts, not just patterns in raw data
Should scientists ditch the social-media platform X?
AI hallucinations are a feature of LLM design, not a bug
Elon Musk has some supporters in science
‘Creepy’ puppets may have starred in rituals at ancient Central American pyramid
Detachable heads of marionettelike figures may have swiveled on a string more than 2000 years ago
‘We have to become self-reliant’: African scientists respond to dramatic U.S. aid cuts
The “brutal” loss of billions of dollars shows Africa should no longer depend on foreign donors, researchers say
Plastic waste in bird nests can act like a tiny time capsule
Expiration dates help biologists trace the building of some avian homes back in history—in one case to 1991
Sticker shock: New U.S. tariffs could raise cost of research equipment and supplies
China, Canada, and Mexico are major suppliers of essential scientific items
NOAA firings hit the birthplace of weather and climate forecasting
Dismissed researchers were improving severe weather predictions
NSF brings back 84 fired workers after judge blocks White House–ordered dismissals
Reinstatements follow scientist’s testimony on how Office of Personnel Management overrode science agency’s decision to retain probationary workers
A systematic review of the therapeutic potential of nicotinamide adenine dinucleotide precursors for cognitive diseases in preclinical rodent models
This systematic review sought to assess the impact of nicotinamide adenine dinucleotide (NAD^(+)) precursors on cognitive impairments in several diseases in rat/mouse models. Accumulating evidence suggests that inflammation, apoptosis, oxidative stress responses, and mitochondrial dysfunction are potential factors of cognitive deficits in aging, Alzheimer's disease (AD), diabetes, traumatic brain injury (TBI), vascular dementia (VAD), and schizophrenia. NAD^(+) precursors have received increased...
Retraction notice to "Enriched environment promotes similar neuronal and behavioral recovery in a young and aged mouse model of Parkinson's disease" [Neuroscience 172 (2011) 443-452]
No abstract
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD
Neuronal cell death is a causative process in traumatic brain injury (TBI)-induced structural and functional impairment of the central nervous system. However, the upstream trigger of TBI-induced neuronal loss and the underlying molecular pathways remain unclear. Zipper-interacting protein kinase (ZIPK) has been shown to be upregulated in Alzheimer's disease and ischemic stroke and to play a role in cellular apoptosis, while its pathological significance in TBI has not been reported. Herein, we...