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Better objective sleep quality is associated with higher gut microbiota richness in older adults
Aging is associated with disrupted sleep patterns, such as fragmented sleep and reduced efficiency, leading to negative health outcomes. There is evidence of a bidirectional relationship between sleep and gut microbiota, which plays a key role in the gut-brain axis and overall health. However, studies on this relationship in older adults have limited generalizability and show conflicting results, highlighting the need for further research. This study aimed to investigate the associations between...
Nocturia as a clinical marker of loss of function and resilience or risk factor for frailty in older adults? Results of the Berlin Aging Study II
The current study examined cross-sectional and longitudinal associations between nocturia and frailty in a cohort of men and women aged 60 years and older, as evidence on this topic was lacking. We analyzed baseline and follow-up data (n = 1671) from the Berlin Aging Study II (BASE-II), a prospective longitudinal cohort study focusing on the factors associated with "healthy" vs. "unhealthy" aging. Self-reported nocturia was dichotomized into < / ≥ 2 micturitions per night, and frailty was...
Combining non-invasive brain stimulation techniques and EEG markers analysis: an innovative approach to cognitive health in aging
In an era marked by a rapidly aging global population, delving into the intricate neurophysiological changes that accompany the aging process assumes paramount importance. This narrative review offers a comprehensive exploration of the intricate relationship between electromagnetic neuromodulation and electroencephalography (EEG) within the context of aging. Moreover, it showed the promising landscape of non-invasive neuromodulation techniques, encompassing established methodologies like...
DEI order grounds NASA program to link undergraduates with mission scientists
Program gave students from underrepresented groups a taste of space science
Nonopioid drug for acute pain wins FDA approval
Ongoing trials will reveal whether suzetrigine is also effective against chronic pain
Daily briefing: Former NIH director Monica Bertagnolli talks Trump
Mitochondria as you’ve never seen them — January’s best science images
‘London Underground’ mosquito has surprisingly ancient origins
Author Correction: Stromal changes in the aged lung induce an emergence from melanoma dormancy
Author Correction: FBP1 controls liver cancer evolution from senescent MASH hepatocytes
Ginkgolide B increases healthspan and lifespan of female mice
A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
Author Correction: Generation of a selective senolytic platform using a micelle-encapsulated Sudan Black B conjugated analog
I’ve been wrongly accused of bullying — what do I do?
‘There is life after burnout in academia’
The AI revolution is running out of data. What can researchers do?
How a wobbly arrow can achieve superpropulsion
US drug agency approves potent painkiller — the first non-opioid in decades
Thousands of highly cited scientists have at least one retraction
Transforming achiral semiconductors into chiral domains with exceptional circular dichroism
Science, Volume 387, Issue 6733, January 2025.