Aggregator
A tough soft-hard interface in the human knee joint driven by multiscale toughening mechanisms
Joining heterogeneous materials in engineered structures remains a significant challenge due to stress concentration at interfaces, which often leads to unexpected failures. Investigating the complex, multiscale-graded structures found in animal tissue provides valuable insights that can help address this challenge. The human meniscus root-bone interface is an exemplary model, renowned for its exceptional fatigue resistance, toughness, and interfacial adhesion properties throughout its lifespan....
Study on the relationship between indoor ventilation frequency and anxiety and depression symptoms in older persons: based on the data of 2018 CLHLS
CONCLUSION: Indoor ventilation frequency is related to depressive symptoms in older persons. Communities and families should pay more attention to indoor ventilation and intervene in time to promote and improve the mental health of older persons.
Daily briefing: What went wrong at 23andMe
‘Do I need to lead this lifestyle to succeed?’ The mental health crises that forced faculty members to change tack
Bluesky’s science takeover: 70% of <i>Nature</i> poll respondents use platform
Star ecologist accused of misconduct loses university post
Rapid in silico directed evolution by a protein language model with EVOLVEpro
Science, Volume 387, Issue 6732, January 2025.
Antarctic krill vertical migrations modulate seasonal carbon export
Science, Volume 387, Issue 6732, January 2025.
Identification of the subventricular tegmental nucleus as brainstem reward center
Science, Volume 387, Issue 6732, January 2025.
Highly multiplexed spatial transcriptomics in bacteria
Science, Volume 387, Issue 6732, January 2025.
Lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension
Science, Volume 387, Issue 6732, January 2025.
Trump’s ban on funds to ‘promote gender ideology’ could threaten hundreds of NIH research projects
Sweeping executive order likely to be read broadly, experts predict
As Trump freeze continues, NIH gets a temporary leader
Agency sees pause on purchases, confusion about publishing, and the end of taxpayer-funded security for Anthony Fauci
Trump pause on foreign aid could threaten distribution of lifesaving drugs, experts say
Health experts worry about impact on major program to combat HIV
Put some wiggle in your mowing. Bees will love it
Cutting grass in ever-changing curves—rather than straight lines—could boost the abundance and diversity of pollinators
Trump tried to destroy a USDA think tank. Here’s what other U.S. agencies could learn from its fate
After the Economic Research Service was moved to Kansas City in 2019, staffing and productivity took a dive
Ancient Roman breastfeeding guidelines were followed closely in the cities—but not the hinterlands
Tooth chemistry shines a light on weaning practices across urban and rural communities in the Roman Empire
Trump’s shutdown of federal diversity office at NSF breaks law that created it
CHIPS and Science Act established position to broaden participation in science
Propagation of pathologic alpha-synuclein from kidney to brain may contribute to Parkinson's disease
The pathogenesis of Lewy body diseases (LBDs), including Parkinson's disease (PD), involves α-synuclein (α-Syn) aggregation that originates in peripheral organs and spreads to the brain. PD incidence is increased in individuals with chronic renal failure, but the underlying mechanisms remain unknown. Here we observed α-Syn deposits in the kidneys of patients with LBDs and in the kidney and central nervous system of individuals with end-stage renal disease without documented LBDs. In male mice,...
alpha-Synuclein deposition in the kidney may contribute to Parkinson's disease
No abstract