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A microRNA is the effector gene of a classic evolutionary hotspot locus
Science, Volume 386, Issue 6726, Page 1135-1141, December 2024.
A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors
Science, Volume 386, Issue 6726, Page 1128-1134, December 2024.
Room-temperature exceptional plasticity in defective Bi2Te3-based bulk thermoelectric crystals
Science, Volume 386, Issue 6726, Page 1112-1117, December 2024.
The complete telomere-to-telomere sequence of a mouse genome
Science, Volume 386, Issue 6726, Page 1141-1146, December 2024.
Programming liquid crystal elastomers for multistep ambidirectional deformability
Science, Volume 386, Issue 6726, Page 1161-1168, December 2024.
A conserved bacterial genetic basis for commensal-host specificity
Science, Volume 386, Issue 6726, Page 1117-1122, December 2024.
Climate change extinctions
Science, Volume 386, Issue 6726, Page 1123-1128, December 2024.
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
Science, Volume 386, Issue 6726, Page 1154-1161, December 2024.
A transient neurohormonal circuit controls hatching in fish
Science, Volume 386, Issue 6726, Page 1173-1178, December 2024.
Active-reset protein sensors enable continuous in vivo monitoring of inflammation
Science, Volume 386, Issue 6726, Page 1146-1153, December 2024.
On the origins of organisms
Science, Volume 386, Issue 6726, Page 1098-1099, December 2024.
Scopes monkey trial, in context
Science, Volume 386, Issue 6726, Page 1100-1100, December 2024.
Why hasn’t the bird flu pandemic started?
Some scientists examining mutations found in H5N1 viruses fear major outbreak is imminent but others say pathogen remains unpredictable
Apex the Stegosaur, the most expensive dinosaur fossil ever sold, heads to a museum
The American Museum of Natural History will host one of the most complete Stegosaurus specimens for the next 4 years
NIH needs a new institute for women’s health research, expert panel says
National Academies report also calls for $16 billion in new money
News at a glance: Orange cats, COVID-19 origin probe, and a collapse of plastic treaty talks
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An overview on the impact of viral pathogens on Alzheimer's disease
Alzheimer's disease (AD) is the most common type of dementia which affects over than 60 million cases worldwide with higher incidence in low and middle-income countries by 2030. Based on the multifactorial nature of AD different risk factors are linked to the condition considering the brain's β-amyloid plaques (Aβ) and neurofibrillary tangles (NFTs) as its primary hallmarks. Lately, viral photogenes specially after recent SARS-CoV-2 pandemic has gained a lot of attention in promoting the...
<em>Hydra</em> has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype
Growing evidence suggests that somatic mutations may be a major cause of the aging process. However, it remains to be tested whether the predictions of the theory also apply to species with longer life spans than humans. Hydra is a genus of freshwater polyps with remarkable regeneration abilities and a potentially unlimited life span under laboratory conditions. By genome sequencing of single cells and whole animals, we found that the mutation rates in Hydra's stem cells are even slightly higher...
Women and aging
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