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Integrated low-temperature PVC and polyolefin upgrading

5 months 3 weeks ago
Science, Volume 390, Issue 6768, Page 88-94, October 2025.
Wei Zhang Boda Yang, Benjamin A. Jackson, Junbo Zhao, Honghong Shi, Donald M. Camaioni, Sungmin Kim Huamin Wang, János Szanyi, Mal-Soon Lee, Jingguang G. Chen, Johannes A. Lercher

No STINGs attached: How APOE-Christchurch dampens Alzheimer's pathology

5 months 3 weeks ago
The "Christchurch" protective variant in the APOE gene has recently been identified, but its mechanisms of action remain unknown. In this issue of Immunity, Naguib and Lopez-Lee et al. provide evidence for the APOE-Christchurch variant suppressing microglial cGAS-STING responses and increasing clearance of pathological tau aggregates in mouse models of Alzheimer's disease.
Leyla Anne Akay