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Daily briefing: A daily multivitamin slows the signs of biological ageing
How ‘Pele’s hair’ sprouts from erupting lava
From cancer to Alzheimer’s: could a renewed focus on energy transform biomedicine?
‘Virtual cell’ captures the most-basic process of life: bacterial division
Stop the use of AI in war until laws can be agreed
How data can help to guide NIH funding policy
Keep calm and be transparent: advice from scientists who retracted their papers
Live parrots were carried across the Andes before the Incas’ rise
Could flies sniff out contraband chemicals?
Alcohol group migration by proximity-enhanced H atom abstraction
Maximizing carrier extraction in hybrid back-contact silicon solar cells
Simultaneous spatial transcriptomics and morphology profiling as tools to explore how microglia change with age
Forget SkinTok: the real science of skincare and why it matters for your health
Privilege, power and vulnerability in science: precarious funding can prompt unethical ties
The ethical risks of open-access agreements being used for authorship leverage
Prevent pandemics through One Health commitments
Artificial general intelligence must be assessed in its scientific and societal context
White House plan to break up iconic U.S. climate lab moves forward
Bidders have lined up to take over pieces of the National Center for Atmospheric Research
Endoplasmic reticulum stress in Parkinson's disease: A pivotal role in cell fate and a therapeutic target
The endoplasmic reticulum (ER) is a central organelle that coordinates protein synthesis and processing, lipid metabolism, Ca²⁺ storage, detoxification, and cellular homeostasis. These processes are rigorously regulated, and when the ER encounters external stimuli, it triggers ER stress, a main mechanism that plays a crucial role in determining cellular fate. In addition to its role in apoptosis, further research has unveiled novel physiological functions of ER stress, encompassing its...
Decoding skin aging: Emerging roles of miRNAs, lncRNAs, and circRNAs in mechanisms, therapies, and future horizons
Skin aging is a multifactorial process influenced by intrinsic and extrinsic factors, including cellular senescence, photoaging, glycation, and impaired wound healing, all of which begin at birth. Recent epigenetic research has identified non-coding RNAs (ncRNAs), particularly microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), as key regulators of gene networks governing skin homeostasis, regeneration, and aging. However, the literature remains fragmented, lacking...