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Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes

3 months 4 weeks ago
CONCLUSION: Increased arterial stiffness and reduced CBF were not independently associated with smaller HV. However, in combination, persistently elevated AS and reduced CBF is associated with smaller HV. These effects were equally exerted across all hippocampal subfields tested. Our findings suggest a lag effect in the arterial stiffness and hippocampal volume relationship. We propose that the subsequent reduction in cerebral blood flow observed with elevated arterial stiffness may be the...
Michelle Horan

Redox-regulated Aux/IAA multimerization modulates auxin responses

3 months 4 weeks ago
Science, Volume 389, Issue 6757, July 2025.
Dipan Roy, Poonam Mehra, Lisa Clark, Vaishnavi Mukkawar, Kevin Bellande, Raquel Martin-Arevalillo, Srayan Ghosh, Kishor D. Ingole, Prakash Kumar Bhagat, Adrian Brown, Kawinnat Sue-ob, Andrew Jones, Joop E. M. Vermeer, Teva Vernoux, Kathryn Lilley, Phil…

Design of intrinsically disordered region binding proteins

3 months 4 weeks ago
Science, Volume 389, Issue 6757, July 2025.
Kejia Wu, Hanlun Jiang, Derrick R. Hicks, Caixuan Liu, Edin Muratspahić, Theresa A. Ramelot, Yuexuan Liu, Kerrie McNally, Sebastian Kenny, Andrei Mihut, Amit Gaur, Brian Coventry, Wei Chen, Asim K. Bera, Alex Kang, Stacey Gerben, Mila Ya-Lan Lamb,…

In Science Journals

3 months 4 weeks ago
Science, Volume 389, Issue 6757, Page 246-248, July 2025.
Michael Funk, and Courtney Malo, Angela Hessler, Phil Szuromi, Di Jiang, Mattia Maroso, Jake S. Yeston, Marc S. Lavine, Caroline Ash, Madeleine Seale, Michael A. Funk, Sarah H. Ross, John Foley, and Christiana N. Fogg