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In Other Journals
Science, Volume 390, Issue 6774, Page 688-689, November 2025.
My family’s sacrifice sustains me
Science, Volume 390, Issue 6774, Page 758-758, November 2025.
The emergence and diversification of dog morphology
Science, Volume 390, Issue 6774, Page 741-744, November 2025.
Earliest oceanic tetrapod ecosystem reveals rapid complexification of Triassic marine communities
Science, Volume 390, Issue 6774, Page 722-727, November 2025.
Layer-by-layer epitaxial growth of perovskite heterostructures with tunable band offsets
Science, Volume 390, Issue 6774, Page 716-721, November 2025.
Clinically ready magnetic microrobots for targeted therapies
Science, Volume 390, Issue 6774, Page 710-715, November 2025.
Integrative phylogenomics positions sponges at the root of the animal tree
Science, Volume 390, Issue 6774, Page 751-756, November 2025.
Electrolytes that reduce electro-osmotic drag improve fast charging of lithium-ion batteries
Science, Volume 390, Issue 6774, Page 745-750, November 2025.
Genomic evidence for the Holocene codispersal of dogs and humans across Eastern Eurasia
Science, Volume 390, Issue 6774, Page 735-740, November 2025.
Branched actin networks mediate macrophage-dependent host-microbiota homeostasis
Science, Volume 390, Issue 6774, Page 728-734, November 2025.
Francis Crick’s life and legacy
Science, Volume 390, Issue 6774, Page 682-682, November 2025.
Meditations on memory
Science, Volume 390, Issue 6774, Page 681-681, November 2025.
Deal to end U.S. shutdown includes good news for farm science funding
Lawmakers reject Trump’s request for deep cuts to research programs
The Trump administration is dismantling efforts to fight the next pandemic
A retreat from investments in drugs and vaccines leaves U.S. less prepared for the next viral scourge, experts warn
Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease
The study of transcriptomic and epigenomic variations in neurodegenerative diseases, particularly tauopathies like Pick's disease (PiD) and Alzheimer's disease (AD), offers insights into their underlying regulatory mechanisms. Here, we identified critical regulatory changes driving disease progression, revealing potential therapeutic targets. Our comparative analyses uncovered disease-enriched noncoding regions and genome-wide transcription factor (TF) binding differences, linking them to target...
Three rising stars in ageing research
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The future of ageing: science aims to deliver another leap in lifespan
No abstract
Is ageing a disease? The debate that could reshape medicine
No abstract
iPEX enables micrometre-resolution deep spatial proteomics via tissue expansion
The number of spatial omics technologies being developed is increasing¹. However, a missing tool is one that can locate proteins in tissues in an untargeted manner at high spatial resolution and coverage. Here we present in situ imaging proteomics via expansion (iPEX), which integrates isotropic tissue magnification² with matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging. iPEX provides scalable spatial resolution down to the micrometre scale and substantially...
circHERC1-A telomerase activator
Telomerase, crucial for maintaining telomere integrity and genomic stability, is typically silenced in somatic cells with advancing age. In this study, we identify circHERC1 as a regulator of telomerase reverse transcriptase (TERT) transcription. Specifically, circHERC1 binds to the TERT promoter, facilitating the recruitment of RNA polymerase II and c-Fos, thereby activating TERT expression. Notably, circHERC1 expression exhibits a decline with age, which correlates with reduced telomerase...