ScienceDaily Health

Scientists reconstructed videos from the brain activity of mice, producing 10-second clips based only on signals from neurons in the visual cortex. The breakthrough could help reveal how the brain reshapes what we see before it becomes our perception of reality.

Eating more ultra-processed foods was linked to greater fat buildup inside thigh muscles, according to MRI scans of 615 adults at risk for knee osteoarthritis. Surprisingly, the association remained even after researchers accounted for calorie intake, physical activity, and other factors. Fatty changes in these muscles may weaken support around the knee and potentially increase osteoarthritis risk.

A naturally occurring molecule called erucamide may help the retina fight back against diseases that cause progressive vision loss. Restoring the molecule activated protective immune responses that helped stabilize retinal tissue and slow aspects of degeneration in preclinical models.

Older adults who changed the balance of fat, carbohydrates, and animal protein in their diets showed signs of reduced biological age after just four weeks. The strongest result appeared in participants eating an omnivorous, lower-fat, higher-carbohydrate diet.

Simply smelling chocolate helped men complete more leg extension repetitions without making the workout feel harder, with dark chocolate producing the strongest effect. The researchers think familiar food aromas may influence appetite and motivation by making the brain anticipate eating.

Scientists have uncovered sweeping changes in how the human brain controls and organizes its genome beginning in midlife, offering new clues to why aging sharply increases the risk of Alzheimer’s and other neurodegenerative diseases. One of the biggest shifts occurred between about ages 50 and 75, when many of the brain’s original immune cells declined and were replaced by cells with more inflammatory characteristics. Researchers also found weakening of cells that help maintain the blood-brain barrier, along with widespread deterioration in the genome’s three-dimensional organization.

The flesh eating New World screwworm has returned to the United States, threatening livestock, wildlife, pets and potentially people as it spreads north. A new UC San Diego tracking system aims to predict where the parasite could strike next while officials revive the eradication strategy that defeated it decades ago.

A major analysis of 139 clinical trials involving nearly 10,000 people suggests that some of the simplest treatments may work best for knee osteoarthritis. Knee braces ranked highest overall for reducing pain, stiffness, and mobility problems, while water-based therapy was especially effective for pain and regular exercise consistently improved both pain and physical function. More high-tech approaches, including ultrasound, generally performed worse.

A newly discovered communication system in the microscopic “antennae” of cells may help explain how some congenital heart defects develop. When genetic mutations disrupt this system, the effects may extend beyond the heart to organs including the brain, kidneys, and skeleton.

Ancient DNA reveals that plague was already killing hunter-gatherers in Siberia 5,500 years ago, long before cities and flea-driven epidemics. The prehistoric strains may have been especially dangerous because they carried a genetic factor capable of provoking severe immune reactions.

Cancer rates are rising in adults under 55, and new research suggests accelerated biological aging may be one piece of the puzzle. Scientists found that people from more recent generations tended to have bodies that appeared biologically older than those of earlier generations at the same chronological age. Greater biological age acceleration was linked to a higher risk of early onset cancers, with specific patterns seen for lung, gastrointestinal, uterine and colorectal cancers.

Scientists have discovered that the brain’s short-range wiring may help protect cognition even as gray matter shrinks with age. Healthier connections just beneath the brain’s surface were linked to better language skills and appeared to weaken the impact of gray matter loss.

A wearable device has revealed nighttime hormone surges that may expose a frequently missed cause of high blood pressure. The discovery could help explain why primary aldosteronism often escapes standard blood tests and point toward a more accurate way to diagnose it.

Low vitamin D levels may make recovery from breast cancer surgery more painful, according to a study of 184 women undergoing mastectomy. Patients with vitamin D deficiency were three times more likely to experience moderate to severe pain during the first 24 hours after surgery and also used substantially more of the opioid painkiller tramadol. They received slightly more fentanyl during surgery and experienced more postoperative nausea as well.

Scientists discovered that aging cells can use malfunctioning mitochondria to unlock inflammatory genes and keep the immune system stuck in a prolonged state of alert. Blocking one part of this process reduced inflammation and improved healthy aging in mice, suggesting a promising new strategy for fighting age-related decline.

Sucralose, the artificial sweetener used in Splenda, came under scrutiny after a study found that a related chemical damaged DNA and weakened the gut barrier in laboratory experiments. But later findings have complicated that alarming picture.

Scientists found that the 3D organization of DNA is disrupted in several types of brain cells affected by Alzheimer’s disease, altering how important genes are switched on and off. The discovery reveals a previously underexplored layer of the disease that could open new paths for understanding and eventually treating Alzheimer’s.

Most men may be missing an important dietary clue about prostate cancer. A new survey found that only 20% knew research has linked dairy consumption with increased prostate cancer risk, while 66% said they would consider avoiding dairy after learning about the connection. Studies have also associated plant-based diets with substantially lower risks of prostate cancer, progression, and recurrence.

AI analysis of 400,000 Reddit posts found that users of drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound reported unexpected symptoms including menstrual changes, chills, hot flashes, and fatigue. Researchers cannot say the medications caused these problems, but the patterns may reveal overlooked signals worth studying.

A natural compound found in foods such as spinach, almonds, and sweet potatoes may aggravate gut inflammation in people with Crohn’s disease and ulcerative colitis because their intestines appear to handle it differently. Researchers say the finding could open the door to lower-oxalate diets or microbiome treatments tailored specifically to people with IBD.