ScienceDaily Health

A psychedelic compound found in magic mushrooms appears to have an unexpected effect: calming highly aggressive fish. Researchers discovered that low doses of psilocybin significantly reduced aggressive attacks in mangrove rivulus fish without disrupting their normal social interactions. The findings suggest psilocybin may selectively calm escalating aggression rather than simply suppressing all behavior.

Researchers have uncovered three brain pathways linked to lasting improvements in people receiving deep brain stimulation for severe, treatment-resistant depression. They also discovered that patients who failed to improve after two years shared a striking pattern: insufficient stimulation of a crucial brain connection. The findings suggest that millimeters in electrode placement could make a major difference in treatment outcomes.

Scientists have uncovered a surprising difference in how male and female skin repairs and renews itself. By tracking individual skin stem cells in living mice for five months, researchers discovered that female cells work together in a highly coordinated way, while male cells operate more independently. This synchronization, driven by sex hormones, helps explain why wounds heal faster in female mice, especially during the first few days.

Scientists have discovered that many common sweeteners can interfere with gut bacteria, with some combinations involving medications producing surprisingly strong effects. One sweetener mixed with a widely prescribed antidepressant reduced beneficial bacteria and microbial diversity in laboratory experiments, raising new questions about potential effects on gut health and immunity.

Scientists have discovered that a protein linked to youth helps protect the brain’s immune cells from age-related decline. Restoring the protein in older mice improved the cells’ ability to clear debris and reduced signs of inflammation, raising hopes for future treatments targeting brain aging and Alzheimer’s disease.

Scientists have discovered that a potential new drug can reverse severe fatty liver disease in animal models by restoring gut health and blocking harmful substances from reaching the liver. The breakthrough could pave the way for new treatments for liver disease and potentially other serious conditions, including cardiovascular disease.

Scientists have uncovered a surprising cause of age-related cognitive decline involving brain cells previously thought to be entirely beneficial. As these cells become dysfunctional, they can produce abnormal amounts of myelin, disrupting nerve fibers and potentially contributing to worsening memory and thinking skills.

Scientists have discovered a surprising two-way relationship between sleep and growth hormone, revealing how the brain carefully balances physical recovery with wakefulness. The findings could help explain why poor sleep harms metabolism and brain health, potentially opening the door to new treatments for sleep and neurological disorders.

Stanford scientists have developed a revolutionary microscope that reveals the hidden inner workings of living cells in real time, without the fluorescent labels that can interfere with observations. The breakthrough could provide new insights into cancer, infectious diseases, and how drugs interact with cells.

USC scientists have discovered a way to create a potentially renewable supply of genetically engineered immune cells that can attack cancer and strengthen the body's natural defenses. By growing and modifying immature immune cells rather than mature ones, researchers developed a system that can continuously produce tumor-fighting cells inside the body.

Yale scientists have uncovered how the stress hormone cortisol helps the brain turn emotional experiences into stronger, longer-lasting memories. The discovery reveals that stress can reshape communication between brain networks involved in emotion and memory, potentially explaining why certain moments are so difficult to forget.

Scientists have discovered how to turn a protein that normally fuels cancer growth into a weapon against it. By activating PPARD in immune cells, researchers made them better at burning fat and attacking tumors, slowing or stopping cancer growth in laboratory experiments. The approach showed promise against colorectal, breast, and ovarian cancers, as well as melanoma.

Scientists have uncovered a hidden biological mechanism that helps explain how exercise can reverse some of the damage caused by muscle aging. The key is a gene called DEAF1, which becomes overactive with age and interferes with the muscles’ ability to clear damaged proteins and repair themselves. Exercise can help restore this balance, allowing older muscles to rebuild and regain strength, although the benefits may diminish when the system becomes too disrupted.

Even under general anesthesia, the human brain can analyze language, recognize different types of words, and predict what comes next in a story, according to a surprising discovery by Baylor researchers. The findings challenge our understanding of consciousness and suggest that the unconscious brain is far more capable than scientists previously realized.

Eating late at night could be putting your liver at risk, according to a large study led by Oregon Health & Science University. Researchers analyzed data from nearly 200,000 people and found that those who regularly ate after dinner or around bedtime had a 20% to 30% higher risk of liver disease, including fatty liver disease and cirrhosis.

Scientists have discovered that unusually small cancer cells carrying extra chromosomes can be far more aggressive than larger ones, growing faster, spreading more readily, and resisting common treatments. The surprising finding could help explain why some tumors are especially dangerous and provide a new way to predict cancer outcomes.

A rare examination of an Alzheimer’s patient’s brain revealed that regions cleared of amyloid plaques had remarkably little of the harmful tau buildup associated with memory loss, while neighboring areas showed extensive damage. The discovery suggests that removing amyloid may have lasting protective effects and could help slow Alzheimer’s progression, especially when treatment begins early.

Strokes are becoming alarmingly common among younger adults, with rates nearly doubling among people ages 20 to 54 over nearly three decades. Researchers found that blocked blood vessels in the brain accounted for much of the increase, while high blood pressure, diabetes, and substance use also became more common among younger stroke patients. Although survival rates have improved, more young adults may now face the lasting consequences of stroke.

Popular diabetes and weight loss drugs such as Ozempic and Wegovy have been linked to a slightly increased risk of a rare condition that can cause sudden, potentially permanent vision loss. Although the risk remains very low, Rutgers researchers say the findings warrant attention as millions of people turn to GLP-1 medications.

A 47-year study has uncovered a surprising turning point in physical aging: fitness and strength begin declining around age 35, even among people who exercise regularly. Researchers found that this decline accelerates as people get older, but starting to exercise in adulthood can still improve physical performance.