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Vitamin C could help block cancer-linked chemicals in your stomach, study finds
Scientists have discovered that vitamin C may help prevent potentially cancer-causing chemicals from forming in the stomach after eating foods containing nitrates and nitrites. A new mathematical model suggests that taking vitamin C after meals could reduce these harmful reactions, offering a possible new strategy for lowering cancer risk.
A common osteoporosis drug blocked spinal damage in a surprising new study
Scientists have uncovered a surprising genetic connection to spinal degeneration and found that an existing osteoporosis drug can prevent damaging mineral buildup in zebrafish spines. The discovery could pave the way for new treatments that slow or prevent a major cause of chronic back pain.
A simple supplement could help your immune system fight cancer and viral infections
A surprising discovery from Rockefeller University suggests that a common amino acid could play a powerful role in protecting against cancer and viral infections. Scientists found that low arginine levels interfere with the immune system's ability to recognize dangerous cells, while increasing arginine intake reduced colon cancer tumors and improved viral infection outcomes in mice. Even more remarkably, giving mice arginine after they contracted influenza helped them recover.
Alzheimer’s may start shrinking two brain regions years before memory loss
Johns Hopkins scientists have uncovered hidden warning signs of Alzheimer’s disease that may appear up to a decade before memory loss begins. Brain scans revealed that two regions involved in memory and emotion start shrinking before the hippocampus, the area doctors typically examine for signs of Alzheimer’s. These early changes are linked to abnormal tau protein buildup and could provide a powerful new way to identify people at risk.
AI discovers a hidden heart signal that could predict sudden death
Scientists have uncovered a hidden warning sign in routine heart scans that could predict sudden cardiac death before it strikes. The AI-powered discovery outperformed conventional screening methods, potentially revealing thousands of people at risk of a fatal heart malfunction that doctors might otherwise miss.
Scientists find a simple daily routine linked to less pain and depression
A simple change to your daily routine could make a surprising difference in how you feel, both physically and mentally. University of Missouri researchers found that older adults who followed consistent daily schedules reported less physical pain and fewer symptoms of depression, even when they struggled with insomnia. Keeping regular times for sleeping, eating, and other activities may help regulate the body's internal clock, which influences mood, sleep, and overall health.
A new fiber supplement could help millions suffering from irritable bowel syndrome
Scientists have developed a promising new fiber supplement that improves gut health in people with irritable bowel syndrome (IBS) without worsening bloating, pain, or other digestive symptoms. The specially designed blend also improved gut-related anxiety and produced surprisingly rapid changes in gut bacteria, potentially offering a new way to manage IBS.
Stanford scientists discover hidden brain signals that predict Alzheimer’s years before symptoms
Stanford researchers have discovered that hidden patterns of brain activity can predict Alzheimer’s risk years before memory problems appear, potentially offering an earlier warning than traditional biomarkers. The same patterns also reveal which brains are unusually resistant to aging, raising hopes for future treatments that could help protect memory.
Exercise after ACL surgery may protect knees from early osteoarthritis
A new study suggests that the right kind of exercise could help protect young adults from early knee osteoarthritis following ACL surgery. Researchers found that a four-month supervised rehabilitation program improved pain, muscle strength, and quality of life without damaging knee cartilage. The findings challenge fears that exercise worsens injured knees and could transform how patients recover from ACL reconstruction.
Predictive performance of lifestyle-informed multimodal brain features for cognition in healthy older adults
Identifying neuroimaging markers of cognitive performance in healthy aging is challenging due to heterogeneity in brain and cognitive characteristics. Among the factors relevant to that heterogeneity are lifestyle choices, of which each individual factor explains only a very small amount of variance in brain and cognition. This challenges current approaches for the prediction of cognitive outcomes. We examined whether brain features associated with an overall lifestyle profile (BF-Life(multi))...
Corrigendum to "CSF and blood glial fibrillary acidic protein for the diagnosis of Alzheimer's disease: A systematic review and meta-analysis" [Ageing Res. Rev. 101 (2024) 102485]
No abstract
Retinography as a marker of the progression of cognitive impairment and/or dementia in older people with type II diabetes mellitus
INTRODUCTION: The aging population increases type 2 diabetes mellitus (T2DM) prevalence and consequently heightens related complications, including dementia and microvascular disease. This study examined the relationship between diabetic retinopathy (DR) and cognitive decline in adults with T2DM.
Linking event-related potentials and structural MRI in the aging brain
Aging alters both brain structure and electrophysiology, which can be measured non-invasively by structural magnetic resonance imaging (MRI) and event-related potentials (ERPs). On average, gray matter declines steadily from early adulthood, whereas white matter increases into midlife before declining. With respect to ERPs, the well-established P300 response shows reduced amplitude and delayed latency from early adulthood onward. Few studies test whether structural MRI and ERP measures correlate...
Resilience-A Concept Toward an Actionable Clinical Approach to Aging
Aging research has increasingly recognized the need for accurate biomarkers of aging, with aging clocks emerging as a powerful tool to quantify the degree of age-related biological change. However, broad clinical implementation and the establishment of wide use of these biomarkers of aging remain ongoing. Resilience reflects a dynamic property of physiological homeostasis and offers a complementary lens to functionally interpret aging. Resilience does not capture the ground state the biological...
Corrigendum to "CSF and blood glial fibrillary acidic protein for the diagnosis of Alzheimer's disease: A systematic review and meta-analysis" [Ageing Res. Rev. 101 (2024) 102485]
No abstract
Yale scientists reveal what really slows aging and what doesn't
Yale researchers have discovered that certain prescription drugs, healthy diets, and exercise can measurably slow biological aging, while popular anti-aging supplements appear largely ineffective. Their analysis of 51 studies could transform how scientists evaluate anti-aging treatments, although whether these biological changes actually extend life remains uncertain.
Forcing yourself to smile can actually make you miserable
Smiling may not always make you happier, and new research suggests that forcing yourself to smile repeatedly could actually make you feel worse. In a University of Florida study involving more than 1,100 participants, researchers discovered that while a single artificial smile can provide a small mood boost, repeatedly faking smiles can erase that benefit or even reverse it.
Scientists discover a hidden danger of viral infections that vaccines may prevent
A new study reveals that viral infections may leave behind hidden damage to the immune system long after symptoms disappear. Researchers found that mice recovering from an acute infection experienced lasting changes to their spleens and weakened immune responses, potentially leaving them more vulnerable to future threats. Surprisingly, prior vaccination completely prevented these harmful changes in the mouse model.
Study of 750,000 pregnancies reveals a surprising twist about Ozempic and Wegovy
A study of more than 750,000 pregnancies found that early exposure to Ozempic, Wegovy, and similar drugs was not linked to increased pregnancy complications when used for weight loss, but was associated with a higher risk of premature birth when prescribed for diabetes. The surprising difference suggests that diabetes itself may be driving the risk, although researchers caution that the drugs' safety during pregnancy remains uncertain.
Stopping statins after 70 may be safer than expected, but there's a catch
A major study of nearly 1,900 older adults suggests that stopping statins after age 70 may be relatively safe in the short term for people who have never experienced a heart attack or stroke. However, a higher rate of serious cardiovascular events or death during longer follow-up raises questions about the risks of discontinuing these widely prescribed medications.