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FDA-approved epilepsy drug may help reverse osteoarthritis damage
Researchers at Yale have identified a promising new approach to osteoarthritis that could do more than simply ease pain. The epilepsy drug lacosamide appears to block a protein involved in both pain signaling and cartilage destruction, helping damaged joints shift back toward repair in preclinical studies.
NIH revives network to study emerging diseases—but its new restrictions baffle scientists
Ban on hunting for new viruses in wildlife is at odds with program’s mission, researchers say
NIH ends 2026 with a boost for early-career researchers, but new awards are down overall
The agency spent its full budget, but left many applicants out of luck
Time-Restricted Feeding Delays Cardiovascular Aging by Increasing Acetic Acid Through Remodeling Gut Microbiota
Time-restricted feeding (TRF) restricts food intake to daily windows, yet its efficacy against vascular aging and underlying mechanisms remain unclear. Here, we demonstrate that TRF attenuates angiotension II -induced accelerated vascular aging by reshaping gut microbiota, stabilizing microbial diversity, and elevating the Firmicutes/Bacteroidetes ratio. TRF preserved intestinal barrier integrity, upregulated tight junction proteins (Occludin, ZO-1, MUC2), reduced serum lipopolysaccharide, and...
Just 7 days of strength training started shrinking fat cells in mice
Just seven strength-training sessions helped obese mice shrink visceral fat cells and reactivate molecular pathways involved in burning stored fat, despite no change in overall body weight. The findings suggest some benefits of resistance exercise may begin long before weight loss becomes visible, though the results still need to be confirmed in humans.
Big dogs age faster than little ones — rogue ‘jumping genes’ might be to blame
Plague scare: what scientists know — and what Russia won’t say
How to build a mouse: Embryo development captured in stunning detail
US proposes $100,000 charge for international students to do post-graduate work
Women are talking about menopause — health systems must listen
Editorial Expression of Concern: Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring
Author Correction: Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity
Heterogeneity in secondary follicle development buffers the lifespan of activated oocytes to optimize female fertility in mice
UAE completes Arab world's first solo space probe <b>– </b>and sets course for an asteroid
Woody ‘blankets’ are being deployed on Arctic permafrost to reduce carbon emissions
Nutritional interventions’ impacts on human milk: Three trials in low-resource settings
Science, Ahead of Print.
A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesis
Science, Ahead of Print.
Shared patterns of human milk composition link mammary gland function to infant growth
Science, Ahead of Print.
Safeguarding global terrestrial vertebrate species from future sea-level rise
Science, Ahead of Print.
A fast radio burst at redshift 2, three billion years after the Big Bang
Science, Ahead of Print.