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Scientists at Stanford may have uncovered a hidden reason our brains decline with age. Studying the ultra-short-lived turquoise killifish, researchers discovered that the cellular machinery responsible for building proteins begins to jam and malfunction over time. Tiny structures called ribosomes start colliding and stalling while reading genetic instructions, triggering a chain reaction that leads to faulty proteins and harmful clumps linked to diseases like Alzheimer’s.

Using cannabis edibles and alcohol together may make drivers far more impaired than either substance alone, according to new research from Johns Hopkins. Even more concerning, common field sobriety tests often failed to detect the cannabis-related impairment.

A sweeping global study found that chronic kidney disease now affects nearly 800 million people and has become one of the world's leading causes of death. Often silent in its early stages, the condition is also a major contributor to heart disease and may be even more common than current estimates suggest.

Vast offshore habitats face threats including mining, trawling, and drilling for oil

Feeling constantly drained might not just be about poor sleep or working too hard. Researchers in Japan found that low levels of key vitamins — especially vitamin B12 and folate — may quietly contribute to fatigue and lack of motivation, even in otherwise healthy people.

Cambridge researchers created miniature brain-and-spinal-cord systems in the lab that can send signals and even trigger tiny muscle contractions. They discovered that human neurons gradually lose their ability to regrow after damage during development — but that ability can potentially be switched back on. The team identified a gene network controlling this process and found that an existing hormone drug dramatically boosted nerve fiber regrowth.

CBD may be doing far more than just easing pain or anxiety — new research suggests it could help fight Alzheimer’s disease by calming the brain’s runaway immune response. In experiments using Alzheimer’s mice, scientists found that inhaled CBD reduced key drivers of neuroinflammation, a damaging process increasingly linked to memory loss and brain degeneration.

Researchers are developing a futuristic alternative to LASIK that reshapes the eye without lasers or incisions. Using mild electrical pulses and platinum contact lenses, they temporarily soften the cornea so it can be molded into a new shape. Early tests on rabbit eyes successfully corrected nearsightedness in about a minute while preserving the eye’s structure.

For more than a century, pianists and music teachers have argued over whether a performer’s touch can actually change the tone color of a piano note — and now scientists say the answer is yes. Using a cutting-edge sensor system that tracked piano key movements at 1,000 frames per second, researchers discovered that elite pianists subtly manipulate keys in ways that listeners can genuinely hear, even if they’ve never played piano before.

Protein homeostasis is essential for maintaining normal cellular function. However, protein homeostasis efficiency declines with age, leading to the accumulation of aberrant protein structures associated with neurodegenerative diseases such as Parkinson's disease (PD). PD is characterized by the aggregation of alpha-synuclein (αSyn) into cytoplasmic inclusions. This process is accompanied by elevated phosphorylation at serine 129 (S129). The accumulation of αSyn into aggregates and their...

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Tauopathies are neurodegenerative diseases characterized by the accumulation of misfolded tau protein and include Alzheimer's disease (AD) and related dementia disorders. Identifying new strategies to treat tauopathy remains an important gap in the field. Using forward and reverse genetic approaches in C. elegans, we identified smrd-1, the C. elegans homolog of SMARCAD1, as a potent modifier of tauopathy phenotypes in a transgenic model of tauopathy. Loss of smrd-1 function rescues...