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Proposed “megaconstellations” would contaminate images from telescopes in low-Earth orbit, including Hubble

Alzheimer's disease (AD) is characterized by progressive memory decline. Converging evidence indicates that hippocampal mRNA translation (protein synthesis) is defective in AD. Here, we show that genetic reduction of the translational repressors, Fragile X messenger ribonucleoprotein (FMRP) or eukaryotic initiation factor 4E (eIF4E)-binding protein 2 (4E-BP2), prevented the attenuation of hippocampal protein synthesis and memory impairment induced by AD-linked amyloid-β oligomers (AβOs) in mice....

CONCLUSION: Future research should focus on longitudinal designs and objective measures to further elucidate the pathways linking multimorbidity, health literacy, and functional health. Fostering the ability to independently obtain, understand and implement health information should be a key goal of clinical practice and policy interventions.

CONCLUSION: Sarcopenia, as defined by AWGS2019 criteria was independently associated with early POCD in elderly individuals after hip fracture surgery. When combined with age ≥ 80 years, it improves the identification of patients at high risk for early POCD.

CONCLUSION: Muscle density mediates the effect of hepatic steatosis on brain aging, supporting its role as a key modifiable factor within the liver-brain axis. These findings underscore the importance of preserving muscle quality to decelerate brain aging.

The Rohingya people have been subjected to egregious human rights abuses, culminating in a mass exodus to the Cox's Bazar district of Bangladesh in 2017. This study investigated the knowledge, attitudes, and practices surrounding older persons within the Rohingya refugee community while also elucidating the present community support mechanisms crucial for their well-being, through a sequential mixed-methods approach. The study specifically focuses on older Rohingya persons aged 60 years and...