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A classic brain test exposed AI's biggest weakness

2 hours 43 minutes ago
Researchers gave top AI models a classic attention test used in psychology and found a major flaw. While the models could correctly name colors in short lists, their performance deteriorated sharply as the task became longer and more complex. Some leading systems fell from over 90% accuracy to nearly complete failure.

Scientists mapped every neural connection in a fruit fly and found a surprise

3 hours 25 minutes ago
A groundbreaking new connectome maps every neural connection in an adult fruit fly’s central nervous system, creating an unprecedented view of how the brain and body work together. The findings suggest that complex behaviors emerge from distributed local circuits rather than a single central controller, offering new clues about intelligence, movement, and brain function.

Cancer patients found a simple way to stay mentally sharp during chemotherapy

12 hours 19 minutes ago
“Chemo brain” affects up to 80% of people receiving chemotherapy, making everyday tasks harder. In a new trial, cancer patients who followed a home-based exercise program showed better attention and fewer noticeable cognitive problems than those who received a placebo. Low-dose ibuprofen also improved some cognitive measures, though its effects were less consistent.

Ultra-processed foods may be stealing your focus even if you eat healthy

1 day ago
A study of more than 2,100 adults found that eating more ultra-processed foods was linked to poorer attention and slower mental processing, even among people with otherwise healthy diets. Researchers also found higher consumption was associated with increased dementia risk factors, raising concerns about the hidden cognitive costs of heavily processed foods.

Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction

1 day 3 hours ago
Excessive alcohol consumption poses significant health risks and is closely associated with oxidative damage. The KEAP1-NRF2-ARE signaling pathway serves as the primary antioxidant system. However, current small molecule inhibitors are all covalently bound to KEAP1, meaning that once bound, they are not easily dissociated, while continuous inhibition of KEAP1 exhibits severe side effects. In this study, BLI, CETSA, Pull-down, Co-IP, and HDX-MS assay analysis were conducted to detect the KEAP1...
Xiaoning Gao

Association between trajectories of physical activity and depressive symptoms among Chinese older adults with chronic disease: evidence from the Chinese Longitudinal Healthy Longevity Survey

1 day 3 hours ago
CONCLUSIONS: Maintaining favorable long-term patterns of PA, even with gradual decline, is associated with reduced odds of DS among older adults with chronic diseases. These findings support PA as a potentially cost-effective strategy for secondary prevention and highlight the importance of sustained behavioral patterns in mitigating mental health risks in aging populations.
Jinghong Huang