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Want to sway an election? Here’s how much fake online accounts cost
Systematic price monitoring sheds light on economics of online manipulation
Autophagy beyond earth: dr. Ghada Alsaleh on aging, cells, and space
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A geological carbon cycle sink hosted by ocean crust talus breccias
Calcium carbonate precipitation in ageing ocean crust sequesters carbon dioxide dissolved in seawater through seafloor weathering reactions, influencing atmospheric CO(2) concentrations on million-year timescales. However, this crustal carbon sink, and the extent it balances CO(2) degassing during crustal formation at mid-ocean ridges, remain poorly quantified due to limited sampling of the vast ridge flanks where CO(2) uptake continues for millions of years. Here we quantify the carbon sink...
Muscle strength and the risk of Multimorbidity in Middle-aged and older Chinese adults: A prospective cohort study
CONCLUSIONS: A low level of muscle strength is significantly associated with an increased risk of comorbidities among middle-aged and older adults. Therefore, incorporating strength training into comorbidity prevention and control strategies is of great importance and should be considered a key intervention. Particular emphasis should be placed on lower limb strength exercises, which do not exhibit a plateau effect in reducing comorbidity risk and can thus yield more substantial health benefits.
Cognitive training effects are shaped more by individual brain dynamics than age-evidence from younger and older women
Given the well-established structural and functional changes in the aging brain, it is widely assumed that cognitive aging is primarily driven by robust group-level differences between young and older adults. However, our individual-level EEG functional connectivity analysis challenges this notion. We investigated the impact of cognitive training on functional brain connectivity using task-switching paradigms in 39 younger (18-25 years) and 40 older (60-75 years) women. Participants were...
Healthy diet and slower biological aging as protective factors against microvascular complications in type 2 diabetes
This study aimed to evaluate the independent and joint effects of adherence to healthy dietary patterns and slower biological aging on the incidence of diabetic microvascular complications in individuals with type 2 diabetes mellitus (T2DM), and to assess the mediating role of biological aging. In a prospective cohort of 13,294 T2DM participants without baseline DMCs, dietary quality was assessed using a validated 10-point score, while biological aging was calculated from nine biomarkers and...
Advances in reproductive technology mean rethinking the meaning of autonomy
Science, Volume 390, Issue 6778, December 2025.
Erratum for the Report “Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode” by J. M. Santos et al.
Science, Volume 390, Issue 6778, December 2025.
Erratum for the Research Article “Cryo–electron microscopy reveals hydrogen positions and water networks in photosystem II” by R. Hussein et al.
Science, Volume 390, Issue 6778, December 2025.
Erratum for the Report “Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice” by A. Ittner et al.
Science, Volume 390, Issue 6778, December 2025.
Multispecies pangenomes reveal a pervasive influence of population size on structural variation
Science, Volume 390, Issue 6778, December 2025.
Cortical glutamatergic and GABAergic inputs support learning-driven hippocampal stability
Science, Volume 390, Issue 6778, December 2025.
Three-component assembly and structure-function relationships of (–)-gukulenin A
Science, Volume 390, Issue 6778, December 2025.
Comparative analysis of human and mouse ovaries across age
Science, Volume 390, Issue 6778, December 2025.
Hepatic leukemia factor directs tissue residency of proinflammatory memory CD4+ T cells
Science, Volume 390, Issue 6778, December 2025.
Locating the missing chlorophylls f in far-red photosystem I
Science, Volume 390, Issue 6778, December 2025.
Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness
Science, Volume 390, Issue 6778, December 2025.