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Sarcopenia and osteoporosis
Sarcopenia and osteoporosis are common, interconnected conditions, in aging populations that lead to increased frailty, disability and a heightened risk of falls and fractures. Sarcopenia is the progressive loss of muscle mass, strength and function, that often coexists with osteoporosis, which is characterized by reduced bone strenght for a decreased bone mineral density (BMD) and altered bone quality. Together, these conditions form a clinical syndrome known as osteosarcopenia. Both disorders...
Obesity and Transition to Assisted Living Services in Older Adults: An Analysis From the National Health and Aging Trends Study
CONCLUSIONS: Overweight, class 1, and class 2 obesity using BMI criteria were protective against TALS. Further study is needed to elucidate the underlying reasons for this protective effect against TALS.
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Gating and noelin clustering of native Ca<sup>2+</sup>-permeable AMPA receptors
Modular arene functionalization by differential 1,2-diborylation
Comprehensive evaluation of plasma tau biomarkers for detecting and monitoring Alzheimer’s disease in a multicenter and multiethnic aging population
Sarcosine decreases in sarcopenia and enhances muscle regeneration and adipose thermogenesis by activating anti-inflammatory macrophages
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Ice society: looking for life at unlikely altitudes
What scientists need to know about sharing—and protecting—their published work
With research papers becoming increasingly free to read and use, understanding open-access licenses is key
How many PhDs does the world need? Doctoral graduates vastly outnumber jobs in academia
Multinational evaluation of AnthropoAge as a measure of biological age in the USA, England, Mexico, Costa Rica, and China: a population-based longitudinal study
We validated AnthropoAge, a biological age (BA) metric, for prediction of mortality and age-related outcomes using harmonized data from the US, England, Mexico, Costa Rica, and China. We estimated AnthropoAge and AnthropoAgeAccel as proxies of BA and age acceleration using body mass index and waist-to-height ratio. We compared mortality prediction of AnthropoAge vs. chronological age (CA) using Cox models and assessed its association with age-related outcomes with generalized estimating...