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Island geography drives evolution of rattan palms in tropical Asian rainforests
Science, Volume 387, Issue 6739, Page 1204-1209, March 2025.
Three-dimensional maps of the interstellar dust extinction curve within the Milky Way galaxy
Science, Volume 387, Issue 6739, Page 1209-1214, March 2025.
Environmental effects of the Kakhovka Dam destruction by warfare in Ukraine
Science, Volume 387, Issue 6739, Page 1181-1186, March 2025.
Geological resource production constrained by regional water availability
Science, Volume 387, Issue 6739, Page 1214-1218, March 2025.
Science at Sundance 2025
Science, Volume 387, Issue 6739, Page 1142-1146, March 2025.
Cryo-EM reveals mechanisms of natural RNA multivalency
Science, Volume 388, Issue 6746, Page 545-550, May 2025.
Structure of human PINK1 at a mitochondrial TOM-VDAC array
Science, Volume 388, Issue 6744, Page 303-310, April 2025.
Is flat 15% fair?
Science, Volume 387, Issue 6740, Page 1258-1259, March 2025.
Homochiral carbon nanotube van der Waals crystals
Science, Volume 387, Issue 6740, Page 1310-1316, March 2025.
NIH reinstates some of its early-career scientists
Agency rehires dozens of probationary staff, but much larger reductions may be looming
Can NIH overturn a court order blocking it from slashing overhead payments? Unlikely, one expert says
An attorney explains where the government erred—and how it could still shrink payments to universities
Implants can help deaf kids hear—but many still struggle with spoken language
Some researchers worry about risks of devaluing sign language, overreliance on imperfect devices
Dinosaur-era mammals’ fur color revealed for first time
Preserved pigments suggest Jurassic mammals had dark fur, consistent with a nocturnal lifestyle
News at a glance: Axing Columbia grants, questioning researchers about socialism, and powering the Voyagers
The latest in science and policy
Wartime destruction of Ukraine dam has set off a ‘time bomb’
Breach of Kakhovka Dam now threatens seasonal floods thick with toxic heavy metals, other pollutants
Fossil face found in Spanish cave belongs to first known Western European
Ancient remains suggest at least two types of early humans roamed Europe about 1 million years ago
Farming wasn’t a wholesale success when it arrived in North Africa
Unlike many Europeans, Stone Age groups in modern-day Tunisia and Algeria weren’t subsumed by the agricultural revolution
Exosomal dynamics: Bridging the gap between cellular senescence and cancer therapy
Cancer remains one of the most devastating diseases, severely affecting public health and contributing to economic instability. Researchers worldwide are dedicated to developing effective therapeutics to target cancer cells. One promising strategy involves inducing cellular senescence, a complex state in which cells exit the cell cycle. Senescence has profound effects on both physiological and pathological processes, influencing cellular systems through secreted factors that affect surrounding...
Unraveling the mystery of citrate transporters in Alzheimer's disease: An updated review
A key molecule in cellular metabolism, citrate is essential for lipid biosynthesis, energy production, and epigenetic control. The etiology of Alzheimer's disease (AD), a progressive neurodegenerative illness marked by memory loss and cognitive decline, may be linked to dysregulated citrate transport, according to recent research. Citrate transporters, which help citrate flow both inside and outside of cells, are becoming more and more recognized as possible participants in the molecular...
Excitatory and inhibitory neurotransmitter alterations with advancing age and injury in the mouse retina
Increasing age and elevated intraocular pressure (IOP) are the two major risk factors for glaucoma, the most common cause of irreversible blindness worldwide. Accumulating evidence is pointing to metabolic failure predisposing to neuronal loss with advancing age and IOP injury. Many neurotransmitters are synthesized from endogenous metabolites and are essential for correct cell to cell signaling along the visual pathways. We performed detailed, small molecule metabolomic profiling of the aging...