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Compressed ionic plastic crystals are cool
Science, Volume 387, Issue 6729, Page 24-25, January 2025.
In Other Journals
Science, Volume 387, Issue 6729, Page 36-37, January 2025.
The classroom door
Science, Volume 387, Issue 6729, Page 110-110, January 2025.
Surface conduction and reduced electrical resistivity in ultrathin noncrystalline NbP semimetal
Science, Volume 387, Issue 6729, Page 62-67, January 2025.
Direct photoreception by pituitary endocrine cells regulates hormone release and pigmentation
Science, Volume 387, Issue 6729, Page 43-48, January 2025.
Sensation is dispensable for the maturation of the vestibulo-ocular reflex
Science, Volume 387, Issue 6729, Page 85-90, January 2025.
Organic ionic plastic crystals having colossal barocaloric effects for sustainable refrigeration
Science, Volume 387, Issue 6729, Page 56-62, January 2025.
Competitive social feedback amplifies the role of early life contingency in male mice
Science, Volume 387, Issue 6729, Page 81-85, January 2025.
Sulfenylnitrene-mediated nitrogen-atom insertion for late-stage skeletal editing of N-heterocycles
Science, Volume 387, Issue 6729, Page 102-107, January 2025.
Tantalum-stabilized ruthenium oxide electrocatalysts for industrial water electrolysis
Science, Volume 387, Issue 6729, Page 48-55, January 2025.
Canadian forests are more conducive to high-severity fires in recent decades
Science, Volume 387, Issue 6729, Page 91-97, January 2025.
Engineering synthetic phosphorylation signaling networks in human cells
Science, Volume 387, Issue 6729, Page 74-81, January 2025.
Bats surf storm fronts during spring migration
Science, Volume 387, Issue 6729, Page 97-102, January 2025.
Data crumbs and sitting ducks
Science, Volume 387, Issue 6729, Page 31-31, January 2025.
Hidden human costs of AI
Science, Volume 387, Issue 6729, Page 32-32, January 2025.
Migrating bats surf warm winds to soar hundreds of kilometers
Tiny transmitters reveal at least one bat species is surprisingly flexible in its migration timing and pathfinding
Better care urged for animal remains tied to Indigenous peoples
New recommendations stress tracing and respecting links between communities and animal bones, pelts, and other remains
Deep learning predicts DNA methylation regulatory variants in specific brain cell types and enhances fine mapping for brain disorders
DNA methylation (DNAm) is essential for brain development and function and potentially mediates the effects of genetic risk variants underlying brain disorders. We present INTERACT, a transformer-based deep learning model to predict regulatory variants affecting DNAm levels in specific brain cell types, leveraging existing single-nucleus DNAm data from the human brain. We show that INTERACT accurately predicts cell type-specific DNAm profiles, achieving an average area under the receiver...
Increased alpha-synuclein phosphorylation and oligomerization and altered enzymes in plasma of patients with Parkinson's disease
The brain of patients with Parkinson's disease (PD) was characterized by increased phosphorylation and oligomerization of α-synuclein (α-syn) and altered activity of enzymes regulating α-syn phosphorylation and oligomerization. Whether increased α-syn phosphorylation and oligomerization as well as related enzyme changes can be detected in the plasma of PD patients remains unclear. Here, we showed that human α-syn proteins incubated in PD plasma formed more oligomerized α-syn (O-α-syn) and...
The effects of loss of Y chromosome on male health
Loss of Y chromosome (LOY) is the most commonly occurring post-zygotic (somatic) mutation in male individuals. The past decade of research suggests that LOY has important effects in shaping the activity of the immune system, and multiple studies have shown the effects of LOY on a range of diseases, including cancer, neurodegeneration, cardiovascular disease and acute infection. Epidemiological findings have been corroborated by functional analyses providing insights into the mechanisms by which...