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My crisis Ph.D.
Science, Volume 387, Issue 6740, Page 1322-1322, March 2025.
Recent gains in global terrestrial carbon stocks are mostly stored in nonliving pools
Science, Volume 387, Issue 6740, Page 1291-1295, March 2025.
Hippocampal encoding of memories in human infants
Science, Volume 387, Issue 6740, Page 1316-1320, March 2025.
Direct effects of mountain uplift and topography on biodiversity
Science, Volume 387, Issue 6740, Page 1287-1291, March 2025.
Macroecological rules predict how biomass scales with species richness in nature
Science, Volume 387, Issue 6740, Page 1272-1276, March 2025.
In-cell architecture of the mitochondrial respiratory chain
Science, Volume 387, Issue 6740, Page 1296-1301, March 2025.
Error-detected quantum operations with neutral atoms mediated by an optical cavity
Science, Volume 387, Issue 6740, Page 1301-1305, March 2025.
Cognitive perception of circulating oxygen in seals is the reason they don’t drown
Science, Volume 387, Issue 6740, Page 1276-1280, March 2025.
Apoplastic barriers are essential for nodule formation and nitrogen fixation in Lotus japonicus
Science, Volume 387, Issue 6740, Page 1281-1286, March 2025.
The animal apothecaries
Science, Volume 387, Issue 6740, Page 1260-1260, March 2025.
Uncertainty abounds, what now?
Science, Volume 387, Issue 6740, Page 1261-1261, March 2025.
NIH council meetings back on, questioning scientists, slow payments at USAID: Trump Tracker
Follow President Donald Trump’s impact on U.S. research and science globally
This fuzzy hummingbird chick may be in disguise—as a caterpillar
Researchers discover rare example of defensive mimicry in birds
‘Pioneering’ study scans babies’ brains as they form memories
Baby-friendly imaging challenges long-standing assumptions about “infantile amnesia”
News at a glance: Flat U.S. research budget, CDC nominee dropped, and who writes review letters
The latest in science and policy
In Mauritius, research monkeys are big business—and big controversy
The island country has become the world’s leading exporter of long-tailed macaques, pitting politicians, conservationists, and neighbors against each other
Deadly fungi are becoming drug-resistant. A new compound could beat them
A drug candidate with a new mechanism of action shows promise against several drug-resistant infections in mice
Neanderthals may have eaten maggots as part of their diet
High nitrogen in Neanderthal bones doesn’t mean they were uber-carnivores
PPDPF preserves integrity of proximal tubule by modulating NMNAT activity in chronic kidney diseases
Genome-wide association studies (GWAS) have identified loci associated with kidney diseases, but the causal variants, genes, and pathways involved remain elusive. Here, we identified a kidney disease gene called pancreatic progenitor cell differentiation and proliferation factor (PPDPF) through integrating GWAS on kidney function and multiomic analysis. PPDPF was predominantly expressed in healthy proximal tubules of human and mouse kidneys via single-cell analysis. Further investigations...
Bcl-xL overexpression in T cells preserves muscle mitochondrial structure and function and prevents frailty in old mice
Our previous transcriptomic analysis revealed an up-regulation of the antiapoptotic protein B cell lymphoma-extra large (Bcl-xL) in centenarians relative to octogenarians or younger cohorts. In this study, we used Bcl-xL-overexpressing mice to assess its impact on successful aging. Our findings indicate that Bcl-xL overexpression modifies T cell subsets and improves their metabolism, apoptosis resistance, macroautophagy, and cytokine production during aging. This more resilient immune system...