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3775-year-old wood burial supports “wood vaulting” as a durable carbon removal method
Science, Volume 385, Issue 6716, Page 1454-1459, September 2024.
Pronouns reactivate conceptual representations in human hippocampal neurons
Science, Volume 385, Issue 6716, Page 1478-1484, September 2024.
Photochemical phosphorus-enabled scaffold remodeling of carboxylic acids
Science, Volume 385, Issue 6716, Page 1471-1477, September 2024.
How wet must a wetland be to have federal protections in post-Sackett US?
Science, Volume 385, Issue 6716, Page 1450-1453, September 2024.
Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation
Science, Volume 385, Issue 6716, Page 1484-1491, September 2024.
Four decades of Hawaiian monk seal entanglement data reveal the benefits of plastic debris removal
Science, Volume 385, Issue 6716, Page 1491-1495, September 2024.
Solar transpiration–powered lithium extraction and storage
Science, Volume 385, Issue 6716, Page 1444-1449, September 2024.
Genetic excision of the regulatory cardiac troponin I extension in high–heart rate mammal clades
Science, Volume 385, Issue 6716, Page 1466-1471, September 2024.
A little care before we leap
Science, Volume 385, Issue 6716, Page 1424-1425, September 2024.
Virtual You: How Building Your Digital Twin Will Revolutionize Medicine and Change Your Life
Science, Volume 385, Issue 6716, Page 1425-1425, September 2024.
Confronting challenges together
Science, Volume 385, Issue 6716, Page 1423-1423, September 2024.
A dynamic mid-crustal magma domain revealed by the 2023 to 2024 Sundhnúksgígar eruptions in Iceland
Science, Volume 386, Issue 6719, Page 309-314, October 2024.
A study found Facebook’s algorithm didn’t promote political polarization. Critics have doubts
Letter to Science questions experiment done during 2020 U.S. elections
Burying wood in ‘vaults’ could help fight global warming
Ancient, preserved log shows how carbon could be locked up for centuries underground
News at a glance: State flowers at risk, a pact on nuclear plant wastewater, and AI uptake
The latest in science and policy
This enigmatic mummy from western China was swathed in cheese
Bronze Age herders were buried with lumps of cheese starter, ancient DNA shows
Barriers to accessing home and community-based services among family caregivers of Veterans
CONCLUSIONS: In addition to known barriers including lack of timely knowledge, service delays, and caregiver stress, Veteran-caregiver disagreements emerged as a novel barrier to using HCBS. A multi-pronged approach that addresses these barriers may increase timely access to HCBS.
Proteomic analysis across aged tissues reveals distinct signatures and the crucial involvement of midgut barrier function in the regulation of aging
The process of aging is a natural phenomenon characterized by gradual deterioration in biological functions and systemic homeostasis, which can be modulated by both genetic and environmental factors. Numerous investigations conducted on model organisms, including nematodes, flies, and mice, have elucidated several pivotal aging pathways, such as insulin signaling and AMPK signaling. However, it remains uncertain whether the regulation of the aging process is uniform or diverse across different...
A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring
Centenarians provide a unique lens through which to study longevity, healthy aging, and resiliency. Moreover, models of human aging and resilience to disease that allow for the testing of potential interventions are virtually non-existent. We obtained and characterized over 96 centenarian and offspring peripheral blood samples including those connected to functional independence data highlighting resistance to disability and cognitive impairment. Targeted methylation arrays were used in...
Proteins required for stereocilia elongation during mammalian hair cell development ensure precise and steady heights during adult life
The hair bundle, or stereocilia bundle, is the mechanosensory compartment of hair cells (HCs) in the inner ear. To date, most mechanistic studies have focused on stereocilia bundle morphogenesis, and it remains unclear how this organelle critical for hearing preserves its precise dimensions during life in mammals. The GPSM2-GNAI complex occupies the distal tip of stereocilia in the tallest row and is required for their elongation during development. Here, we ablate GPSM2-GNAI in adult mouse HCs...