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Electrical coherent driving of chiral antiferromagnet

10 months ago
Science, Volume 389, Issue 6762, Page 830-834, August 2025.
Yutaro Takeuchi, Yuma Sato, Yuta Yamane, Ju-Young Yoon, Yukinori Kanno, Tomohiro Uchimura, K. Vihanga De Zoysa, Jiahao Han, Shun Kanai, Jun’ichi Ieda, Hideo Ohno, Shunsuke Fukami

Control of immune response in an iPSC-based allogeneic cell therapy clinical trial for Parkinson's disease

10 months ago
Because the central nervous system (CNS) is an immune-privileged organ, it requires different immunosuppression strategies for cell therapies using induced pluripotent stem cells (iPSCs) compared with ones for organ transplantations. We recently conducted the first in-human clinical trial of a cell therapy for Parkinson's disease using allogeneic iPSCs (jRCT number: jRCT2090220384). All patients were transplanted with dopaminergic neural progenitors differentiated from iPSCs (iPSC-DANs), which...
Asuka Morizane