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Obesity and Transition to Assisted Living Services in Older Adults: An Analysis From the National Health and Aging Trends Study
CONCLUSIONS: Overweight, class 1, and class 2 obesity using BMI criteria were protective against TALS. Further study is needed to elucidate the underlying reasons for this protective effect against TALS.
Daily briefing: Space shots from the largest digital camera in the world
Trump team vows to improve kids’ health: scientists are sceptical
The shattered statues of Queen Hatshepsut: the reasons for the wreckage
Will Gates and other funders save massive public health database at risk from Trump cuts?
Obesity drugs show promise for treating a new ailment: migraine
Did the US wipe out Iran's nuclear programme? What researchers know
Gating and noelin clustering of native Ca<sup>2+</sup>-permeable AMPA receptors
Modular arene functionalization by differential 1,2-diborylation
Comprehensive evaluation of plasma tau biomarkers for detecting and monitoring Alzheimer’s disease in a multicenter and multiethnic aging population
Sarcosine decreases in sarcopenia and enhances muscle regeneration and adipose thermogenesis by activating anti-inflammatory macrophages
Tardigrade-obsessed: meet the researchers trying to turn water bears into neuroscience models
‘Natural history museums can save the world’: anti-colonialism, conservation and climate change
Medical AI can transform medicine — but only if we carefully track the data it touches
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Ice society: looking for life at unlikely altitudes
What scientists need to know about sharing—and protecting—their published work
With research papers becoming increasingly free to read and use, understanding open-access licenses is key
How many PhDs does the world need? Doctoral graduates vastly outnumber jobs in academia
Multinational evaluation of AnthropoAge as a measure of biological age in the USA, England, Mexico, Costa Rica, and China: a population-based longitudinal study
We validated AnthropoAge, a biological age (BA) metric, for prediction of mortality and age-related outcomes using harmonized data from the US, England, Mexico, Costa Rica, and China. We estimated AnthropoAge and AnthropoAgeAccel as proxies of BA and age acceleration using body mass index and waist-to-height ratio. We compared mortality prediction of AnthropoAge vs. chronological age (CA) using Cox models and assessed its association with age-related outcomes with generalized estimating...
Mechano-energetic uncoupling in heart failure
Heart failure (HF) is a major global and life-threatening disease. Despite advances in therapies, the prevalence of HF is increasing owing to an ageing population and the pervasive pandemic of obesity and metabolic disorders, which have transformed the pathophysiology of HF. Changes in cardiac energy metabolism and the related energy deficit crucially contribute to the severity and type of HF. Furthermore, perturbations in excitation-contraction coupling, mitochondrial function and oxidative...