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Senescent Microglia Mediate Neuroinflammation-Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1
Microglia-mediated neuroinflammation has been shown to exert an important effect on the progression of a growing number of neurodegenerative disorders. Prolonged exposure to detrimental stimuli leads to a state of progressive activation and aging-related features in microglia (also termed as senescent microglia). However, the mechanisms by which senescent microglia contribute to neuroinflammation-induced cognitive dysfunction remain to be elucidated. Here, we developed a mouse model of...
Exploration of the effects of Tai Chi practice on lower limb corticomuscular coherence during balance-demanding virtual reality conditions in older adults
Tai Chi practice has been widely adopted to improve balance and prevent falls in older adults. However, the neural mechanisms underlying the benefits of Tai Chi are difficult to evaluate during traditional balance assessments. The goal of this study was to evaluate the effects of Tai Chi and healthy aging on corticomuscular coherence (CMC) while standing in virtual balance-demanding environments. We recorded neural, muscular, and behavioral data in an immersive virtual reality environment while...
Some butterflies adapted to have second ‘heads’ that confuse predators
A new evolutionary analysis of butterflies finds “false heads” arose from the coalescence of multiple traits
Elephants gesture to signal what they want—just like us
New experiments show elephants use a wide range of movements to express their desires