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ADHD, at 42
Science, Volume 387, Issue 6741, Page 1430-1430, March 2025.
A wheat tandem kinase activates an NLR to trigger immunity
Science, Volume 387, Issue 6741, Page 1402-1408, March 2025.
Selective filtering of photonic quantum entanglement via anti–parity-time symmetry
Science, Volume 387, Issue 6741, Page 1424-1428, March 2025.
Full freedom-of-motion actuators as advanced haptic interfaces
Science, Volume 387, Issue 6741, Page 1383-1390, March 2025.
A high-temperature nanostructured Cu-Ta-Li alloy with complexion-stabilized precipitates
Science, Volume 387, Issue 6741, Page 1413-1417, March 2025.
Abrupt sea level rise and Earth’s gradual pole shift reveal permanent hydrological regime changes in the 21st century
Science, Volume 387, Issue 6741, Page 1408-1413, March 2025.
A wheat tandem kinase and NLR pair confers resistance to multiple fungal pathogens
Science, Volume 387, Issue 6741, Page 1418-1424, March 2025.
High-frequency location data show that race affects citations and fines for speeding
Science, Volume 387, Issue 6741, Page 1397-1401, March 2025.
A geographic history of human genetic ancestry
Science, Volume 387, Issue 6741, Page 1391-1397, March 2025.
An end to human exceptionalism
Science, Volume 387, Issue 6741, Page 1360-1360, March 2025.
The meaning of our meals
Science, Volume 387, Issue 6741, Page 1359-1359, March 2025.
Genetic surprise gives horses exceptional endurance
A mutation that should have cut a protein short instead makes it more sensitive to the stress of exercise
News at a glance: Collider’s last run, early galaxy’s oxygen, and climate authors sought
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Activity-dependent regulation of Cdc42 by Ephexin5 drives synapse growth and stabilization
Synaptic Rho guanosine triphosphatase (GTPase) guanine nucleotide exchange factors (RhoGEFs) play vital roles in regulating the activity-dependent neuronal plasticity that is critical for learning. Ephexin5, a RhoGEF implicated in the etiology of Alzheimer's disease and Angelman syndrome, was originally reported in neurons as a RhoA-specific GEF that negatively regulates spine synapse density. Here, we show that Ephexin5 activates both RhoA and Cdc42 in the brain. Furthermore, using live imaging...