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Correction for Matsuzaki et al., Transcriptional drift in aging cells: A global decontroller
No abstract
Age-Related Dynamics and Spectral Characteristics of the TCRbeta Repertoire in Healthy Children: Implications for Immune Aging
T-cell receptor (TCR) diversity is crucial for adaptive immunity, yet baseline characterizations in pediatric populations remain sparse. We sequenced the TCRβ chain of 325 healthy Chinese children aged 0-18, categorized into six age groups. We also analyzed cellular composition and TCRβ associations using flow cytometry in 81 of these samples. Our results indicate a decrease in TCRβ diversity with age, characterized by an increase in high-frequency clonotypes and notable changes in CDR3 length...
Investigating the Role of TRPV4 and GPR35 Interaction in Endothelial Dysfunction in Aging Mice
Endothelial dysfunction, characterized by a decline in endothelial physiological functions, is a significant aspect of cardiovascular aging, contributing notably to arterial stiffness, atherosclerosis, and hypertension. Transient receptor potential channel V4 (TRPV4), a key member of Ca^(2+)-permeable channels, plays a crucial role in maintaining vascular functions. However, the role and mechanisms of TRPV4 in aging-related endothelial dysfunction remain incompletely understood. Here, we...
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Author Correction: Genetics of female and male reproductive traits and their relationship with health, longevity and consequences for offspring
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Beyond misalignment of science in the news and in schools
Science, Volume 387, Issue 6729, January 2025.
Chronic stress induces senescence build-up early in life
Restoring aging-related tissue homeostasis via reactivated innate immunotherapy
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Science, Volume 387, Issue 6729, Page 35-37, January 2025.
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Trump names AI-focused team as leaders of his science office
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