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Cross-tissue comparison of epigenetic aging clocks in humans
Epigenetic clocks are a common group of tools used to measure biological aging-the progressive deterioration of cells, tissues, and organs. Epigenetic clocks have been trained almost exclusively using blood-based tissues, but there is growing interest in estimating epigenetic age using less-invasive oral-based tissues (i.e., buccal or saliva) in both research and commercial settings. However, differentiated cell types across body tissues exhibit unique DNA methylation landscapes and age-related...
Deprescribing in Older Adults With Type 2 Diabetes: Associations With Patients' Perspectives: The Diabetes and Aging Study
CONCLUSIONS: Patients' perspectives may enable or hinder deprescribing, emphasizing the importance of soliciting these perspectives during shared decision-making. Effective deprescribing will benefit from understanding patients' perspectives and fostering patient-provider communication about medication changes throughout the disease course.
Daily briefing: Meet <i>Punk</i> and <i>Emo</i>, the 430-million-year old mollusc fossils
Repurposing of a gill gene regulatory program for outer ear evolution
Revealed: the fatty cells that are the ‘bubble wrap’ of the body
Who’s quitting academia? Data reveal gender gaps in surprising fields
Male spiders smell with their legs
Grazing can reduce wildfire risk amid climate change
Science, Volume 387, Issue 6730, January 2025.
Why the last cases of sleeping sickness will be the hardest to eliminate
Author Correction: Progressive plasticity during colorectal cancer metastasis
Scientists unlock secrets of ear’s origin and construction
Studies suggest mammals’ external ears carry unexpected type of cartilage and rely on the same genetic instructions as gills
Seeking disease insights, UK Biobank launches largest study of human proteins
Measuring levels of thousands of proteins in the blood of half a million people could suggest treatments and diagnostic tools, researchers say
In Science Journals
Science, Volume 387, Issue 6730, Page 149-151, January 2025.
Retraction
Science, Volume 387, Issue 6730, Page 147-147, January 2025.
Impacts of EPA’s finalized power plant greenhouse gas standards
Science, Volume 387, Issue 6730, Page 140-143, January 2025.
Optimism for a global plastics treaty
Science, Volume 387, Issue 6730, Page 119-119, January 2025.
How a neurotransmitter drives brainwashing during sleep
Science, Volume 387, Issue 6730, Page 127-127, January 2025.
NIH sets out to double check biomedical studies
Science, Volume 387, Issue 6730, Page 126-126, January 2025.
Dogs sniff out truffles—in the name of science
Science, Volume 387, Issue 6730, Page 124-125, January 2025.
‘Good boring’: How Bluesky is shaping scientists’ discourse
Science, Volume 387, Issue 6730, Page 123-124, January 2025.