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Low-iridium device speeds progress towards green hydrogen
Atlantic oceanic droughts do not threaten Asian water tower
Reply to: Atlantic oceanic droughts do not threaten Asian water tower
Publisher Correction: Skin autonomous antibody production regulates host–microbiota interactions
Paracrine FGF21 dynamically modulates mTOR signaling to regulate thymus function across the lifespan
Enhanced paracrine action of FGF21 in stromal cells delays thymic aging
FGF21 keeps the thymus young
What’s next for the World Health Organization? US exit could reshape agency
Cycles
Exclusive: These universities have the most retracted scientific articles
Why retractions data could be a powerful tool for cleaning up science
Women need platforms to celebrate excellence in research and technology
Why these scientists devote time to editing and updating Wikipedia
Author Correction: Seasonal advance of intense tropical cyclones in a warming climate
Newfound bat virus that uses notorious receptor poses ‘spillover’ risk
Ax falls on elite group of Ph.D.s training to lead U.S. public health labs
Most of the fellows in CDC’s highly competitive Laboratory Leadership Service were fired last weekend
Judge recommends lifting Florida’s ban on hiring students from China
2023 law bars students from China and six other countries from graduate assistant and postdoc positions at state universities
Do mysterious ultra-energetic cosmic rays come from colliding neutron stars?
Mergers may create dynamos that rev up the universe’s most energetic particles
Rab27b promotes lysosomal function and alpha-synuclein clearance in neurons
Alpha-synuclein (αsyn) is the key pathogenic protein implicated in synucleinopathies including Parkinson's Disease (PD) and Dementia with Lewy Bodies (DLB). In these diseases, αsyn is thought to spread between cells where it accumulates and induces pathology; however, mechanisms that drive its propagation or aggregation are poorly understood. We have previously reported that the small GTPase Rab27b is elevated in human PD and DLB and that it can mediate the autophagic clearance and toxicity of...
Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST
Ergothioneine (EGT) is a diet-derived, atypical amino acid that accumulates to high levels in human tissues. Reduced EGT levels have been linked to age-related disorders, including neurodegenerative and cardiovascular diseases, while EGT supplementation is protective in a broad range of disease and aging models. Despite these promising data, the direct and physiologically relevant molecular target of EGT has remained elusive. Here, we use a systematic approach to identify how mitochondria...