The transcription factor Bcl11a is essential for B-1a cell maintenance during aging Aging & Longevity
Impact of cognitive decline on the physical functioning of older adults in Southern Brazil: a cross-sectional study Aging & Longevity
BubR1 Insufficiency Drives Transcriptomic Alterations and Pathology Associated With Cardiac Aging and Heart Failure Aging & Longevity
Centenarians and near-centenarians in India: empirical insights on health and well-being characteristics Aging & Longevity
Analysis of health information needs of elderly patients with chronic diseases based on Kano Model: a descriptive cross-sectional study Aging & Longevity
Association between community-based health services and health lifestyles of older adults: evidence from China Aging & Longevity
Transforming aged care in China: insights from a TF-IDF-based data mining analysis of national policies (2018-2022) Aging & Longevity
Development and validation of a predictive model for sarcopenia risk in older Chinese adults based on key factors Aging & Longevity
Journal plagued with problematic papers, likely from paper mills, pauses submissions Science Daily Headlines
NIH restores grants to South Africa scientists, adds funding option for other halted foreign projects Science Daily Headlines
Genetic evidence that our brains make new neurons in adulthood may close a century-old debate Science Daily Headlines
Researchers claim their AI model simulates the human mind. Others are skeptical Science Daily Headlines
Exclusive: Famed protein structure competition nears end as NIH grant money runs out Science Daily Headlines
Should grant applicants judge competitors’ proposals? Unorthodox approach gets two real-world tests Science Daily Headlines
Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression Science
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition Science
Illuminating microbial dark matter: Dietary alterations uncover microbial regulation of immunity and metabolism Science
Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies Nature Aging
DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease Nature Aging
Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosis Nature Aging
A TFEB–TGFβ axis systemically regulates diapause, stem cell resilience and protects against a senescence-like state Nature Aging
Clusterin drives myeloid bias in aged hematopoietic stem cells by regulating mitochondrial function Nature Aging
Senescent macrophages induce ferroptosis in skeletal muscle and accelerate osteoarthritis-related muscle atrophy Nature Aging
Age-dependent accumulation of mitochondrial tRNA mutations in mouse kidneys linked to mitochondrial kidney diseases Nature Aging
Comprehensive evaluation of plasma tau biomarkers for detecting and monitoring Alzheimer’s disease in a multicenter and multiethnic aging population Nature Aging
Advances, challenges, and opportunities of human midbrain organoids for modelling of the dopaminergic system Alzheimer & Parkinson
Increased risk of dementia and its subtypes following various forms of acquired brain injury: a meta-analysis and systematic review Alzheimer & Parkinson
Rethinking TREM2 as a target for Alzheimer's disease after the INVOKE-2 trial failure Alzheimer & Parkinson
A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis Alzheimer & Parkinson
Ultradeep N-glycoproteome atlas of mouse reveals spatiotemporal signatures of brain aging and neurodegenerative diseases Alzheimer & Parkinson
HDL-bound S1P affects the subventricular niche and early neuropathological features of Alzheimer's disease Alzheimer & Parkinson
An O-glycopeptide participates in the formation of distinct Aβ<sub>42</sub> fibril structures and attenuates Aβ<sub>42</sub> neurotoxicity Alzheimer & Parkinson
Glial reactivity correlates with synaptic dysfunction across aging and Alzheimer's disease Alzheimer & Parkinson