The emerging role of dysregulated propionate metabolism and methylmalonic acid in metabolic disease, aging, and cancer Aging & Longevity
Metformin delays the decline in thermogenic function of brown adipose tissue in a mouse model of Hutchinson-Gilford progeria syndrome Aging & Longevity
Rhythms and shifts of chemokines and cytokines interplay in a decade lifespan: The longitudinal community-based Bambui health and aging study Aging & Longevity
Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging Aging & Longevity
Stability of locus coeruleus cell counts despite volume loss in cognitively impaired aged rhesus macaques Aging & Longevity
Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice Aging & Longevity
Chromatin remodeler CHD4 establishes chromatin states required for ovarian reserve formation, maintenance and male germ cell survival Aging & Longevity
An ancestor of ducks and geese paddled and dove alongside dinosaurs in Antarctica Science Daily Headlines
‘It’s tectonic:’ U.S. foreign aid freeze deals a blow to research around the globe Science Daily Headlines
Carbon monoxide blamed for deaths of 22 research monkeys at troubled supplier Science Daily Headlines
Scratching promotes allergic inflammation and host defense via neurogenic mast cell activation Science
Hippocampal coding of identity, sex, hierarchy, and affiliation in a social group of wild fruit bats Science
Erratum for the Review “Addressing interconnect challenges for enhanced computing performance” by J.-S. Kim et al. Science
Multi-omic profiling of sarcopenia identifies disrupted branched-chain amino acid catabolism as a causal mechanism and therapeutic target Nature Aging
Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging Nature Aging
Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial Nature Aging
A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice Nature Aging
Author Correction: Generation of a selective senolytic platform using a micelle-encapsulated Sudan Black B conjugated analog Nature Aging
Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells Nature Aging
Author Correction: Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types Nature Aging
Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging Alzheimer & Parkinson
HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses Alzheimer & Parkinson
Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes Alzheimer & Parkinson
Reducing microglial lipid load enhances beta amyloid phagocytosis in an Alzheimer's disease mouse model Alzheimer & Parkinson
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression Alzheimer & Parkinson
Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical protein kinase C in the anterior cingulate cortex Alzheimer & Parkinson
A central role for acetylcholine in entorhinal cortex function and dysfunction with age in humans and mice Alzheimer & Parkinson
Uncovering dark mass in population proteomics: Pan-analysis of single amino acid polymorphism relevant to cognition and aging Alzheimer & Parkinson